Compact multi-synthesis radiosynthesizer
The MultiSyn is the most compact, versatile and easy to use disposable cassette radiosynthesizer.
Easy GMP compliance.
The sterile disposable synthesis cassette and reagent set helps avoid cross-contamination and ensures reproducible results
This enables you to effortlessly meet the most stringent quality control and GMP compliance standards
By using non-proprietary components, the user can modify and develop their own cassettes.
Low metal contaminant materials are used.
Lower your labs consumable costs with low priced cassettes and reagents.
Typical Synthesis Route
The MultiSyn can perform the following synthetic steps, or you can setup your own method by simply modifying the hardware cassette and synthesis recipe.
Elution of the isotope to the MultiSyn
Step 2: (Optional)
Pre-purification of the eluted/delivered isotope
S.P.E. purification and reformulation of the labelled product
Final injectable radiotracer
Delivery of the isotope to the MultiSyn
One synthesizer for all your radiochemistry needs.
Standardize and simplify your labs radiochemistry requirements with the one versatile synthesizer. By simply changing the hardware cassette, you can easily switch to another radiosynthesis without any cross-contamination.
Compatible with all Ga-68 Generators.
The MultiSyn is compatible with all commercial Ga-68 generators.
The MultiSyn has a built-in force limiting syringe drive for generator elution and can perform no pre-purification, as well as cationic or anionic pre-purification of the generators eluate.
Direct Elution Labelling
The simplest 68Ga synthesis method involves direct labelling of the generators eluate.
This method reduces synthesis time and simplifies system setup.
Certain reactions require reduction of the acid concentration of the generator eluate and or purification of metal impurities (such as 68Ge) from the eluate to improve reaction conditions.
This is easily accomplished with generator pre-purification and involves trapping the generator eluate onto a purification cartridge and subsequent elution to the reactor with a >99% trap and release efficiency of 68Ga.
Other Radiometal Labelling
The MultiSyn can used for a number of different radiometals such as 64,67Cu, 89Zr.
Optimized synthesis recipes.
...more isotopes and tracers to come!
*Decay corrected radiochemical yields.
Uncorrected yields: [Ga-68]PSMA = 80.5%, [Ga-68]DOTA-TATE = 74.7%
Easily install multiple synthesizers in the one hotcell.
External Control Electronics
Eliminate radiation damage
The MultiSyn's PLC (programmable logic controller) electronics are housed in an external enclosure located outside of the hotcell.
This eliminates the possibility of damage to the electronic components due to high radiation fields thereby significantly increasing system reliability.
Open User Interface
System control & visual synthesis recipe development all in one platform.
The user interface combines both powerful features, yet easy to use tools for both daily operation and synthesis recipe development.
Easy to use open software interface for easy tracer development
Guides you step-by-step during the synthesis
Can be installed on multiple computers for remote synthesis
Recording of all process variables and report generation (21 CFR Part 11 & GMP compliant)
Traditional PC or Touch Screen Tablet Control
Built-in remote diagnostics enabling simplified troubleshooting
Open software system comes standard at no extra cost to the user
Generate and print synthesis reports to satisfy you labs documentation and GMP requirements
Real-Time Sensors Trends
All sensor information can be displayed graphically in real-time trends
Historical Data Review
Review previous synthesis results as trend graphs with data analysis function
Graphical Synthesis Recipe Development
Click • Define • Save
1. Click Schematic
Click schematic elements such as solenoid valves and rotary actuators to turn them on/off or to set positions.
2. Define parameter
Define parameters such as reactor temperatures, syringe volumes & step parameters (description, time, condition).
3. Save Step
Click the Save Step button and the software will automatically fill-in the Excel recipe step list automatically.
Synthesis recipes are stored as easily editable Excel step list files
Some of the institutions that are using the MultiSyn.
Key aspects of our support structure
Complete stock of spare parts for all synthesizers are available and can be expressed shipped to you to minimise downtime.
The field of radiochemistry is
ever changing and our education program is there to ensure your team is fully up to date with our latest developments.
You are always a phone call or an email away from an experienced iPHASE engineer or staff member to assist with any queries. Achieving customer satisfaction is our primary objective.
Due to the ever evolving nature of technology, we are continually following the trends and applying the latest technologies to our systems to increase performance, productivity and reliability.
Remote diagnostics are built into every system we make. This enables our experienced engineers to diagnose, test and guide the user to the quickest solution to an issue should it arise.
Hands on Training
Personalized hands on training will ensure your staff will easily learn and master all aspects of our automated technology.
About iPHASE technologies
iPHASE technologies is a world class designer and manufacturer of automated instrumentation for P.E.T. radiochemistry. By using the latest automation technologies coupled together with intelligent design and class leading software interfaces, our instrumentation is built by users for users.